Taking down a Domination Rex is not an easy feat. Using a Brachiosaurus is also a viable method, as their mega stomp attack can output large amounts of damage. The use of a leveled Giganotosaurus, a well bred Rex, or a Magmasaur may prove essential in the defeat of a Domination Rex. The Domination Rex can also utilize its pin ability to instantly kill smaller creatures. Its ability to camouflage similar to a Rock Drake coupled with its Movement Speed allows it to easily ambush enemies. An imprinted and leveled Domination Rex can prove quite dangerous, and in some situations, deadly.

The Domination Rex is a formidable opponent in battle. This section describes how to fight against the Domination Rex. This means it is currently impossible to make alterations to the Domination Rex's colors. The Domination Rex always spawns with the same color scheme and has no color regions. The Domination Rex also has the ability to camoflauge. However, its arms are a lot larger than those of the Rex, and sport four large claws. The Domination Rex is white and similar in appearance to a Rex. The Domination Rex attacks everyone and everything when it is maturing, even the survivor who imprinted on it.

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